The results confirmed the long-term safety, efficacy, accuracy, and predictability of ICL implantation for hyperopia. The Collamer material was well tolerated in all eyes.
Because of the incomplete follow-up, we cannot draw conclusions about the long-term safety of the implantable contact lens. The intimate contact between the contact lens and the natural lens raises the possibility of cataract formation. However, examination by Scheimpflug photography and ultrasound biomicroscopy showed no progressive lens opacities.
FIRS make KC cornea more regular and the patients have increased corrected and uncorrected visual acuity postoperatively. The progression of KC was stopped and the cornea thickness minimally, but regularly, improved.
The activity of alkaline ribonuclease (RNase), of RNase inhibitor and the level of inhibition have been measured in transparent human lenses of different age and in senile cataracts. While a free RNase activity was never found in clinically clear lenses, the level of RNase inhibitor decreases with age and may even be absent in very old lenses. Cataractous lens homogenates have lost the capacity to inhibit exogenous RNase but sufficient inhibitor remains to inactivate a significant fraction of the endogenous enzyme. The level of intralenticular electrolytes has no direct influence on the activity of the RNase inhibitor.
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