This article documents the case history of a 9-year-old Brazilian child diagnosed with Kabuki make-up syndrome (KMS). The clinical features are described, with emphasis on the craniofacial and orodental manifestations. The patient had the distinctive KMS craniofacial features consisting of long palpebral fissure, hypertelorism, high-arched eyebrows with sparse hair in the lateral one-third, eyes with eversion of the lateral one-third of the lower eyelids, long and curved eyelashes, palpebral ptosis, large anteverted prominent ears in a lower position, broad, depressed nasal root with a flat nasal tip, and mild neuropsychomotor developmental deficits. The intraoral examination revealed an anterior open bite, overretention of primary teeth, and a high-arched palate. Two findings in this child have not been previously reported in patients with KMS: the presence of supernumerary teeth and taurodontic teeth in the maxillary arch. The clinical and radiographic detection of these unique dental features may be helpful in identifying children who may have milder forms of KMS.

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Introduction Implantable cardiac pacemakers or cardioverter defibrillators are alternatives for the treatment of arrhythmias, however, their use has caused changes in the emotional state of patients. The objective of this study was to compare the measures of anxiety and depression symptoms in individuals according to their sex, type of cardiac device, and diagnosis of Chagas disease. Methods This is an observational and cross-sectional study conducted with adults with implantable cardiac pacemakers or cardioverter defibrillators. Data was collected using a sociodemographic and clinical questionnaire and the Hospital Anxiety and Depression Scale. We used the Student’s t-test for independent samples and the Chi-squared test, with a significance level of 0.05. Results Two hundred forty-four patients participated in the study, 168 with cardiac pacemakers and 76 with implantable cardioverter defibrillators; 104 had Chagas cardiomyopathy (85 with cardiac pacemakers and 19 with implantable cardioverter defibrillators). No statistically significant differences were found in measures of anxiety and depression symptoms according to device type (P=0.594 and P=0.071, respectively) and the presence of Chagas etiology (P=0.649 and P=0.354, respectively). Women had higher mean scores for anxiety (P=0.002) and depression symptoms (P<0.001). Conclusion In the comparison between the groups, according to the type of implanted device and the diagnosis of Chagas disease, no significant differences were found in the measures of anxiety and depression symptoms. Women showed higher means when compared to men, indicating the need to test and implement interventions to minimize these symptoms in this population.

This study evaluated, by SEM, the morphology of human primary teeth roots. Twenty-four teeth were divided into 3 groups: pulp vitality (group I) and pulp necrosis without (group II) and with apical periodontitis (group III). Roots were analyzed by the presence of periodontal ligament (PDL) fibers and resorption areas. In groups I and II, presence of PDL fibers and absence of resorption were observed in all cases (100%), while all specimens (100%) of group III showed no PDL fibers and resorption areas. In conclusion, there are morphological differences in the apical region of primary teeth with different pulpal and periapical pathologies.

O presente estudo objetiva analisar as publicações científicas de alto impacto que avaliaram a qualidade de vida relacionada à saúde de pacientes com câncer de próstata em tratamento radioterápico. Para tanto, ancora-se num estudo exploratório, de revisão integrativa da literatura, utilizando as bases de dados PubMed, Web of Science, Scopus e Lilacs, com os descritores: Quality of life, Prostatic neoplasms e Radiotherapy, usando o operador booleano AND. Do total de 1418 artigos localizados, foram excluídos 1403 após o uso dos filtros adotados como critérios de inclusão e exclusão, de acordo com cada base de dados, e leitura dos respectivos resumos, resultando em 15 artigos. Os resultados evidenciaram que o tratamento de radioterapia causa impacto na qualidade de vida relacionada à saúde dos pacientes, com manifestações de sinais e sintomas de intensidade variada, principalmente nas funções urinária, sexual e intestinal. Mesmo havendo declínio na qualidade de vida relacionada à saúde durante o tratamento, os efeitos negativos foram limitados e temporários, podendo melhorar com o passar do tempo. Ainda que os estudos tenham sido realizados em momentos e países diferentes, com amostras, modalidades de radiação e instrumentos distintos, os resultados contribuíram para o planejamento, a execução e avaliação do tratamento radioterápico no cotidiano dos serviços oncológicos, considerando a realidade de cada um. Recomenda-se a realização de novas pesquisas de modo a possibilitar a identificação dos efeitos dos diferentes tipos de radiação e suas consequências na vida dos pacientes, com vistas à escolha de medidas terapêuticas menos impactantes.