The development of a diffuse elastic tissue defect resembling pseudoxanthoma elasticum (PXE) is a recently established and frequently encountered clinical entity in beta-thalassemia. The clinical spectrum of this disorder is not yet completely understood as it is continuously being enriched with novel complications that are often serious. We present here a thalassemia intermedia patient with typical PXE manifestations and a fusiform aneurysmatic dilatation of the ascending thoracic aorta, a previously unknown complication in these patients. An aortic aneurysm has itself a notable morbidity, while it may also impair the particularly susceptible cardiac function of beta-thalassemia patients, hence affecting the overall prognosis of the main disease.
información del artículoHistoria del artículo: Recibido el 3 de febrero de 2016 Aceptado el 3 de marzo de 2016 On-line el 18 de abril de 2016Palabras clave: Rasgos psicopáticos Estudio longitudinal Conducta antisocial Agresión reactiva y proactiva r e s u m e n En este trabajo se analizan los datos de un estudio longitudinal a largo plazo con el objetivo de examinar las implicaciones de los rasgos psicopáticos infanto-juveniles, evaluados a través de la mCPS (modified Child Psychopathy Scale), en la conducta antisocial en la adolescencia. Se analizan los datos recogidos en 141 niños (edad media = 7.80), que fueron seguidos seis y diez años más tarde. Los resultados muestran que los niños con altas puntuaciones en rasgos psicopáticos presentan en la adolescencia temprana niveles relativamente altos de problemas de conducta. Además, a lo largo de la adolescencia se produce en ellos un mayor incremento en implicación con amigos antisociales, consumo de cannabis y agresión proactiva. Así, los resultados muestran que los rasgos psicopáticos medidos en la niñez se asocian con un desarrollo más desfavorable, particularmente en indicadores que, como la agresión proactiva, se han vinculado clásicamente a la personalidad psicopática en adultos.
a b s t r a c tThis research analyzes data from a long-term longitudinal project with the aim of studying the implications of childhood psychopathic traits (measured through the mCPS; modified Child Psychopathy Scale) in adolescent antisocial behavior. Data from 141 children (mean age = 7.80), followed-up six and ten years later, were analyzed. Results indicate that children high in psychopathic traits show relatively high levels of behavioural problems in early adolescence. Moreover, throughout adolescence they show a higher increase in their involvement with antisocial peers, cannabis use, and proactive aggression. Thus, results show that psychopathic traits measured in childhood are linked to a more unfavorable development, particularly to indicators classically associated to adult psychopathic personality (e.g., proactive aggression).
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