Lethal midline granuloma (Stewart's syndrome, midline reticulosis) earlier was a name given to all progressive destructive lesions involving the nose, paranasal sinuses, hard palate, face, orbit, and upper airway. With the advent of immunohistochemistry, it is evident that it comprises a heterogenous group of disorders including non-Hodgkin lymphoma, Wegener's granulomatosis, and various granulomatous conditions which can often be encountered with dilemma of diagnosis.
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