The single nucleotide polymorphism (SNP) at Trp53arg72 pro genotypes is found to be associated with breast cancer, with variable results, the aim of this study is to evaluate the frequency of SNP at Trp 53 codon 72 and its association with breast cancer in north Indian population. Methods: 30 patients with breast cancer were compared with 30 controls. Genotype and allele distribution of Trp53 codon 72 where determined using polymerase chain reaction-restriction fragment length polymorphism method.
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