These findings suggest that prophylactic hysterectomy with bilateral salpingo-oophorectomy is an effective strategy for preventing endometrial and ovarian cancer in women with the Lynch syndrome.

No abstract

We found that the majority of patients diagnosed with endometrial cancer at a young age were obese and nulliparous. In addition, we found a high incidence of synchronous primary ovarian cancers in this cohort of young, premenopausal women.

This paper presents an integrated system designed to obtain a high‐resolution image via super‐resolution image reconstruction by using an observer of a motorized head under control. An advantage of this integration is that the constructed system can algebraically and systematically calculate the registration and motion blur identification, which is quite different from the way in which the conventional methods preprocess captured images. To illustrate the effectiveness of the presented system, some experimental results are provided. © 2013 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.

In this prospective study of endometrial cancer patients younger than age 50 years, 9% were found to carry germline Lynch syndrome-associated mutations. In addition to young age of onset, family history, BMI, and molecular tumor studies can improve the likelihood of identifying a Lynch syndrome-associated germline mutation in MLH1, MSH2, and MSH6.