A simple synthesis of D- and L-apiose using the aldol condensation of furanose with formaldehyde under alkaline conditions as a key reaction is described.
Alkyl halides are important intermediates in organic synthesis. The conversion of alcohols into their corresponding halides is frequently a useful and necessary synthetic operation.
A simple conversion of the previously described (1) tricyclic ester 1 into the pentacyclic songorine intermediate 21 is described. The process is stereospecific and it operates in an overall yield of 7.8z.On prtsente une mtthode simple pour transformer I'ester tricyclique 1 dtcrit prtctdemment en intermediaire pentacyclique 21 de la songorine. Le proctde est sttreosptcifique et effectut avec un rendement global de 7.8z.[Traduit par le journal]Can. J . Chern., 51,3978 (1973) We have described recently (1) a simple synthesis of the tricyclic ester 1 via the sequence i 4 ii -, iii -, iv -,
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