Carcinoma of the larynx is uncommon in children 15 years of age or younger. Because of low index of suspicion, the diagnosis of childhood laryngeal carcinoma is often delayed. Other factors contributing to its delayed diagnosis are the similarity of its early symptoms to those of other benign, common childhood conditions and the relative difficulty encountered during pediatric laryngeal examination. Treatment of pediatric laryngeal cancers is challenging, because no guidelines are available. We believe that every single case of childhood laryngeal cancer should be reported, because of paucity of literature on this childhood entity, it is limited only to case reports and reviews. This makes treatment options and outcomes difficult to interpret.
Solitary fibrous tumors (SFT) rarely occur in the neck region and can be easily mistaken for more common tumors if the index of suspicion is not high. They are characterized by remarkable histologic variability. However, immunopositivity for CD34 and Bcl2 with immunonegativity for other markers aid in establishing the diagnosis. Distinction from the other common benign entities is essential, as SFT are tumors of low grade aggressiveness and unpredictable biologic behavior. Complete resection is the key feature determining outcome.
We report a case of nonsyndromic type of multiple basal cell carcinoma associated purely with actinic keratoses. A 69-year-old Indian male had suffered from multiple, variable-sized papules and nodules on the face, neck and chest for 13 years previous to treatment. He had no history of arsenic intake, irradiation, herb medication, or exposure to chemical warfare gases. Family histories for basal cell carcinoma and xeroderma pigmentosum were negative. Classical features of Gorlin's syndrome were conspicuous by their absence. Histopathologically, the tumors revealed typical findings of basal cell carcinoma arising from actinic keratoses. The case in point is a very rare and unique case in itself as being nonsyndromic, nonhereditary and occurring in the absence of various other environmental conditions as already mentioned in literature.
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