MicroRNA(miRNA)s have been identified as an emerging class for therapeutic interventions mainly due to their extracellularly stable presence in humans and animals and their potential for horizontal transmission and action. However, treating Type 2 diabetes mellitus using this technology has yet been in a nascent state. MiRNAs play a significant role in the pathogenesis of Type 2 diabetes mellitus establishing the potential for utilizing miRNA-based therapeutic interventions to treat the disease. Recently, the administration of miRNA mimics or antimiRs in-vivo has resulted in positive modulation of glucose and lipid metabolism. Further, several cell culture-based interventions have suggested beta cell regeneration potential in miRNAs. Nevertheless, few such miRNA-based therapeutic approaches have reached the clinical phase. Therefore, future research contributions would identify the possibility of miRNA therapeutics for tackling T2DM. This article briefly reported recent developments on miRNA-based therapeutics for treating Type 2 Diabetes mellitus, associated implications, gaps, and recommendations for future studies.

In the contemporary generation, rapid urbanization, industrialization, and declining woodland lead to global weather modifications. The massive scale of deforestation for firewood, constructions, paper products, textile, and plenty of different packages are steadily enforcing a critical poor impact on the surroundings. Inherently, plant cellulose has restrained utility because of the presence of hemicellulose and lignin. Consequently, studies in the discipline of microbial cellulose display many benefits over plant cellulose. It possesses numerous crucial and unique properties compared to plant cellulose, including high purity, better absorptivity, excellent polymerization, crystallization, in-situ mold potential, biodegradability, biocompatibility, and plenty of others. This assessment looks into a potent cellulose producer to develop an economically feasible manner for huge-scale production of microbial cellulose therefore, it may replace some of the requirements where plant cellulose has been currently in use.