While topical NSAIDs as a class may be associated with severe adverse events, such events appeared to require potentiation in the form of high total doses, ocular comorbidities, or both with Acular and Voltaren. Severe adverse events might have been more likely to occur at lower doses and in routine postoperative settings with generic diclofenac.

There have been no comprehensive investigations of striae after LASIK. The ophthalmic literature has few reports, and no one consistent therapy has been recommended. Striae are relatively uncommon; nevertheless, refractive surgeons need a systematic approach in prevention and therapy for striae. Careful flap handling and positioning can prevent many striae. Early recognition is very important and makes treatment significantly more likely to eliminate or reduce the striae. If the striae are identified within 24 hours, lifting and refloating will likely result in resolution of the striae. If the striae are more imbedded and have been present longer, additional techniques, such as those discussed, are helpful. New techniques will likely be developed because of an increase in lamellar procedures and an increase in the occurrence of striae.

No abstract