Currently, chronic dermatoses have become widespread in the population, while it is often not possible to achieve the desired effect of the therapy. The analysis of modern literature data indicates a high prevalence of gastrointestinal diseases among patients with a dermatological profi   On the one hand, a skin lesion can be a valuable differential diagnostic criterion for early diagnosis of digestive tract pathology. On the other hand, the common origin at the early stages of ontogenesis determines the development of a number of diseases with simultaneous damage to both the digestive organs and the skin. The presented review evaluates the relationship of skin pathology with the state of the digestive tract, and also considers the feasibility of including additional measures aimed at the diagnosis and treatment of diseases of the gastrointestinal tract in the management of patients with chronic dermatoses.