It has been suggested that antioxidant systems are impaired in pregnancy induced hypertc, nsion and hence patients are exposed to oxidative stress. In order to investigate the relationship between lipid peroxidation and certain antioxidant parameters in blood of pregnancy induced hypertension (PIH) cases, 25 normotensive and 23 PIH samples were studied. In the present study, thiobarbitudc acid reactive substances showed a tendency to increase, however the increase remained statistically insignificant. Plasma ascorblc acid level remained unaltered and Vitamin E showed a tendency to increase in the study group. The findings implicate oxidative stress in the disease and cite the biochemical rationale for clinical trials of antioxidants to prevent and treat pregnancy induced hypertension.
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