Changes in serum CTX levels seem to predict the potential for tumour control and the likelihood of developing an SRE in a sample of patients with solid tumours and bone metastases treated with ZA.

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Breast cancer is the most frequent neoplasia in women. Randomized studies which compare mastectomy with conservative treatment show no differences in global survival. In cases in which conservative surgery is performed, breast radiation therapy and boost reduces the rate of local recurrence. On March 2010, the 8th Consensus Meeting of the Spanish Society for Radiation Oncology (SEOR) Brachytherapy Group was held in Madrid about «Treatment of Breast Cancer with Brachytherapy». In this article we presented the conclusions about brachytherapy boost, Partial breast irradiation and clinical dosimetry.