Acute toxicity, accumulation and histological effects produced by various concentrations of platinum (H2PtCl6) in the intestine of Brachydanio rerio were investigated. Degenerative (lysis and necrosis of mucosal cells, changes in submucosa structure) and adaptative (fusion between villi) responses were revealed. The extent and the severity of the intestinal alterations were time‐ and concentration‐dependent. Intestinal recovery was noted after 15 days of exposure to a sublethal Pt concentration (16 μg/L) followed by 64‐day depuration. The characterization of the intestine responses in fish that were experimentally exposed to Pt can provide a basis for recognizing toxicity syndromes and should in fine be of use in the early prognosis of the effects of environmental aquatic Pt pollution.
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