The new generation of glucose biosensors has gained immense research interest owing to its cost effectiveness, quick response, good stability, reproducibility, and low detection limit. The enzymatic glucose sensor suffers from numerous intrinsic disadvantages; therefore, there is a need to develop a new biosensor which can overcome the disadvantages of enzymatic glucose biosensors. In that context, metal oxide-based nanostructures and their compostites exhibit properties that can overcome the drawbacks of enzymatic glucose sensors. This review discusses recent developments in some of the metal oxides (CoO, NiO, CuO, and ZnO) along with their composites as well as their applications toward nonenzymatic glucose sensors. The metal oxide composites possess excellent features which signify the potential commercial applications of metal oxide-based composites for nonenzymatic electrochemical glucose sensing.

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