Objective:To compare the therapeutic cure rate and adverse reactions in the regimens of the Revised National Tuberculosis Control Program (RNTCP) with directly observed treatment, short-course (DOTS) and without DOTS.Materials and Methods:Fifty patients in the DOTS regimen and 50 patients in the non-DOTS regimen were enrolled in the study. All the participants were asked to come regularly for 3 consecutive days for sputum collection, and the sputum samples were examined for acid-fast bacilli. If tuberculosis (TB) was confirmed, the disease status was confirmed through a chest X-ray (PA view). The participants were monitored for adverse events arising from the use of anti-TB drugs for the next 6 months.Results:The TB cure rates for RNTCP with DOTS and RNTCP with non-DOTS were 80% and 66%, respectively. The DOTS therapy had a better cure rate for radiologically positive, sputum-positive cases compared with the non-DOTS regimen group. The non-DOTS treatment regimen had significantly increased numbers of adverse events in the hepatic and hematinic systems.Conclusion:The DOTS regimen has higher cure rates and a lower incidence of adverse reactions compared with the non-DOTS regimen.
In India, Project Portfolio Management (PPM) is in practice as a tool for prioritizing and managing real estate projects in construction organizations. But due to insufficient funding, improper judgment of experts during the crisis situation, the selection of optimal project portfolio prototype can be viewed as a risk based decision making process involving various risk factors. The objective of this study is to analyze the importance of project portfolio management and the risks associated with it in the construction industry taking into account the impact of novel corona virus COVID 19. This research identifies the adoption of more consistent project governance, risk management techniques and way more careful project portfolio management as the core area of study. A conceptual framework for Project Portfolio Management is also designed after analyzing various parameters of Project Portfolio Management of construction industry with the help of Bayesian framework. The key motive for undertaking this part of examination on real estate sector of Indian construction industry in southern part of India to reduce the impacts and increase the return on investment from the projects by mitigating the effect of risk factors associated in the projects. Project Portfolio Management tools and techniques are very useful for managing multiple construction projects.
Operational efficiency directly reflects the profitability of a project. It is for benefit of a construction site. The current research paper focus on high operational efficiency by reducing waste, better layout planning, sound administration, business practices an, review of existing facilities etc. To improve the operational efficiency will enhance the profit by adding the value to the project in the form of cost reduction in internal transportation, utilization of existing facilities effectively. The study adopted the Computerized Relative Allocation of Facilities Techniques (CRAFT) and computerized relationship planning (CORELAP) algorithm to analyze the operational efficiency.
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