El desarrollo del sistema nervioso es un proceso complejo que tiene como resultado la maduración de las estructuras, la adquisición de habilidades y, finalmente, la formación del individuo como persona única. La presente revisión recoge información acerca de las principales características de los procesos de desarrollo cerebral, las características del desarrollo neurológico normal en las diferentes áreas: motora gruesa y fina, lenguaje, sensorial y socialización; se acompaña también de una descripción de las principales alteraciones en el desarrollo, identificables en la consulta diaria del pediatra. Nuestro objetivo es reforzar el conocimiento en esta área clave de la evaluación del niño menor de cinco años para detectar problemas con la debida antelación para su intervención oportuna.
factors interfere with adolescents's social behavior. Hormonal synthesis, synaptogenesis, synaptic remodeling and myelination are the underlying causes of changes in specific brain areas (prefrontal, temporoparietal, insula, cingulate gyrus and amygdala), which are related to executive functions and social cognition improvements. Conclusion: Biological studies concerning brain changes during adolescence allow us to better understand these individuals' behavior, helping society look for more effective ways to deal with teenagers and create methods which contribute to cognition and sociability development.
of disease. The virus caused focal coagulative necrosis in liver, spleen, kidney, lung and testis and widespread mild vascular damage. In brain there was intense congestion, with erythrocyte 'sludging', but no inflammatory reaction, significant injury to microvasculature in all organs. Virus replicated in endothelial cytoplasm causing focal necrosis, separation of tight junctions and detachment from basement membranes. These changes were associated with oedema and haemorrhage, contributing to hypovolaemic shock were not sufficiently extensive to account for severity of vascular collapse.Therefore, alongside with chest and abdominal pain, cough, conjunctivitis, jaundice, pancreatitis, lymphadenopathy, delirium, and coma, other complications after second week of infection include transverse myelitis and encepalitis.
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