nowadays information is shared through online resources. It is necessary to provide security to the shared information. To maintain the secrecy of the information shared various techniques are used. Enabling multiple encryptions will disable the interloper to recover the information and to strengthen the security multi fold. Multiple Encryption are performed by shifting the particular block of the image using quantum polarization states, then the shifted output are coded using Convolution encoder and finally encrypted using Rubik's encryption algorithm. Result analysis was performed for DICOM images based on the statistical and security analysis.
In this study, 3-D structures of Harpin protein (Pectobacterium carotovorum), Single-stranded DNA binding protein (Pseudomonas aeruginosa), and R2.LlaJI (Campylobacter conisus 13826) has been modelled. For modelling, template selection is done by BLASTp search. For target template alignment, ClustalW server is used and then comparative modelling was done by Modeller9.10. Validation of models was done by PROCHECK and ProSA-web. After this, the best model out of all, for each of the proteins was selected and their active sites was obtained using CASTp. Core drug was selected by literature search and different leads were designed for the target proteins using MARVIN SKETCH. Docking was done by HEX5.1 followed by AutoDock4. The best lead selected after this study can serve as pharmacophores for the designing of potential drugs against diseases.
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