Elevated glucose concentrations during an oral glucose tolerance test are associated with the presence of metabolic syndrome in childhood obesity Sabin MA, Hunt LP, Ford AL, et al.
In recent years there have been several major changes to the diagnosis and management of diabetes mellitus. The World Health Organisation (WHO) recommended the use of haemoglobin A1C as a diagnostic marker of diabetes in 2011. HbA1C measurement has been standardised to International Federation of Clinical Chemistry (IFCC) methods and is now being reported in IFCC units. This recommended change was implemented in the UK from 1 June 2009, but is yet to be embraced internationally. We assessed the impact of these changes on the use of HbA1C and oral glucose tolerance tests (OGTT) in the primary care population. We found a decrease in OGTT tests requested/performed with a concurrent increase in the number of samples with HbA1C < 48 mmol/mol (< 6.5%) received in the laboratory. This changing practice of diabetes testing in our primary care antedates the WHO recommendation.
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