<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Foot dermatoses are a common malady in children. It has a varied presentation ranging from patchy fissured scaly lesions to disabling highly inflammatory vesicular eruption. A role for foot wear exacerbating these dermatoses is a possibility, which could be confirmed by patch testing.</span><span lang="EN-IN">To evaluate the role of patch testing in determining the allergen either causing or exacerbating various foot dermatoses in children.</span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">Patch testing was done in 40 children with various foot dermatoses using the standard footwear series and the results were read after 48 hours, 96 hours and again after 7 days. Also, skin biopsy was done in 10 cases from the representative lesions</span>.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Patch test was positive in 24(60%) patients to different antigens. Disperse orange (25%) was found to be the commonest allergen followed by epoxy resin (15%), neomycin sulphate (12.5%) and black rubber mix (10%). </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Patch testing has a major role in finding out the causative agent or at least the exacerbating footwear in various foot dermatoses. Disperse orange was found to be the most common allergen. The diagnosis of acrodermatitis or JPD should not deter doing a patch testing.</span></p><p> </p>
<p class="abstract"><strong>Background:</strong> Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are considered as the severest end of spectrum of erythema multiforme. Various etiologies like infections, drugs and malignancies have been proposed. The aim of the present study was to know the incidence, common causes, clinical course of SJS and TEN and to estimate the morbidity and mortality<span lang="EN-IN">.</span></p><p class="abstract"><strong>Methods:</strong> A 2 year study of patients presenting with SJS and TEN was carried out. A detailed examination to know the cutaneous and mucosal involvement was done. Biopsy was done in 3 patients.<strong></strong></p><p class="abstract"><strong>Results:</strong> There were fifty patients of SJS-TEN spectrum. Of which 31 were SJS, 3 had SJS-TEN overlap and 16 had TEN. Anticonvulsants were implicated in causing these reactions in 24 patients (48%) with carbamazepine being the most common i.e. in 16 patients (32%). Sparing of pressure areas like the strap area of brassier and waist was noticed in two patients (4%). The most common complication was due to eye involvement seen in 20 patients (40%). 46 patients were treated with steroids and of the remaining, 3 were children and one was HIV positive. Only three patients with TEN (6%) died<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> To conclude, TEN was less common than SJS, had more sequelae and more mortality compared to SJS<span lang="EN-IN">.</span></p><p class="abstract"> </p>
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