Accepted for publication 6th October, 1993. Arthroscopic surgery is one of the most commonly performed orthopaedic procedures, and is promoted as of_ feting many advantages over open surgical procedures, including less patient discomfort and pain, shorter hospitalization, and quicker rehabilitation.~ There ave few reports of pain after arthroscopic procedures.2 However, previous studies have suggested that non-steroidal antiinflammatory drugs (NSAIDS) may decrease the inflammarion associated with arthroscopie procedures, probably due to the inhibition of prostaglandin synthesis, thus reducing pain and speeding recovery. 3 To evaluate the role of prostaglandim in post-arthroscopy pain, several studies have evaluated the use of the anri-prostaglandin nonsteroidal anti-inflammatory drugs in reducing arthros-CAN J ANAESTH 1994 / 41:2 / pp98-101
to changes in PaCO 2 between 27-50mmHg remains intact during propofol anaesthesia in healthy individuals. Our absolute CBF values are similar to those previously reported during fixed dose propofol anaesthesia but are lower than those we haye recorded during propofol-N20 anaesthesia ~,z. Similarly, the slope of CBF-PaCO 2 relationship is less than during propofol-N20 anaesthesia. These differences may be explained by either the c e r e b r o v a s o d i l a t i n g e f f e c t of N20 or the quantity of propofol used. During hypocapnia, CBF was low, but there were no changes clinically or in the evoked potentials to suggest ischaemia. Propofol may therefore reduce the CBF threshold for cerebral isohaemia as assessed by evoked potentials.
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