17-ketosteroids urinary elimination as well as corticotropin Thorn test have been studied in 46 patients affected with neoplastic diseases. In monocentric tumours (epithelial and connective-tissue tumours of any organs with unifocal development) a decreased urinary elimination of androgen metabolites and a normal response to Thorn test were observed. On the contrary, an apposite functional behaviour of the adrenal cortex was demonstrated in systemic tumours, resulting in an abundant elimination of urinary 17-ketosteroids and absent fall of hematic eosinophils after corticotropic stimulation. Some interpretative hypotheses are advanced.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.