In the article, within the framework of intellectualization of the Lean Production technology, it is proposed to optimize the costs arising from the insufficient efficiency of placing goods in the warehouse by creating an optimization method based on the immune metaheuristics of the T-cell model, which allows solving the knapsack constrained optimization problem. The proposed metaheuristic method does not require specifying the probability of mutation, the number of mutations, the number of selected new cells and allows using only binary potential solutions, which makes discrete optimization possible and reduces computational complexity by preventing permanent transformations of real potential solutions into intermediate binary ones and vice versa. An immune metaheuristic algorithm based on the T-cell model has been created, intended for implementation on the GPU using the CUDA parallel information processing technology. The proposed optimization method based on immune metaheuristics can be used to intellectualize the Lean Production technology. The prospects for further researches are to test the proposed methods on a wider set of test databases.
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