Further follow-up may define an acceptable low-risk group for breast relapse. Until then, we recommend that all patients receive breast irradiation. Systemic adjuvant therapy should be considered for patients with poor nuclear grade tumors.
Summary. A patient is described with invasive squamous carcinoma developing in one cervix in a didelphic uterus with double cervix and vagina completely separated by a vaginal septum.
Summary.-We have determined that when an extract of human brain is preincubated with lymphocytes its subsequent capacity to inhibit the electrophoretic mobility of tanned and stabilized erythrocytes is much reduced. There is a differential effect, however, as the observed reduction is from 73% inhibition to 35% when the pre-incubation is with lymphocytes from patients with malignant disease, but from 73% to 10% when it is with lymphocytes from normal controls. These values were obtained at a brain extract concentration of 333 I&g/ml, with 5 x 106 lymphocytes, a pre-incubation time of 18-24 h, and a temperature of 27°C, which are the optimum conditions determined for differentiation between cancer patients and normal subjects. In a series of 73 subjects tested by this method 43/51 cancer patients gave an unequivocal "positive" value, 22/22 normal controls gave a "negative" value, with no false positives.
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