In 28 fetuses studied during a 4 1/2-year period, the initial femur was below 2 standard deviations (SDs) of the mean when compared with the biparietal diameter. These fetuses were considered at risk for skeletal dysplasias and were followed up. Studies were performed at a mean gestational age of 26.7 weeks (range, 15.3-41.0 weeks). Group 1 had a femur length 1-4 mm below the 2-SDs line (range, -2.0 to -4.0 SDs); no other abnormalities were detected. Interval examination of 12 femurs showed that 10 either remained shortened to the same degree or had a growth spurt. At birth, all subjects were healthy except one with mild growth retardation and one with a chromosomal abnormality. Of the two subjects that failed to continue normal growth, one was healthy and the other was a heterozygous achondroplastic dwarf. Group 2 had greater femoral shortness; all measurements were more than 5 mm below the 2-SD line (range, -4.3 to -31.0 SDs). All had fetal abnormalities and significant skeletal dysplasias. The authors conclude that the number of millimeters below the 2-SDs line is an accurate, easy criterion for evaluation of femoral length.
The location of the boundaries among the endometrium, inner myometrium (dark), and outer myometrium (intermediate or bright) were compared on T2-weighted magnetic resonance (MR) and intravaginal ultrasound (US) images obtained within 24 hours of each other. Twelve women with normal reproductive cycles underwent a total of 21 pairs of examinations. The endometrium, inner myometrium (junctional zone), and outer myometrium were measured by three independent observers. The endometrial thickness was thinner with MR imaging (6.5 mm with MR imaging vs 7.9 mm with US early in the cycle [P = .001]; 9.9 mm with MR imaging vs 11.3 mm, respectively, late in the cycle [P = .045]). The junctional zone was thicker with MR imaging (4.4 vs 2.3 mm early [P less than .001]; 3.9 vs 2.2 mm late [P = .003]). The combined thickness of the endometrium and junctional zone was thicker with MR imaging (15.5 vs 12.7 mm early [P = .002]; 17.3 vs 15.8 mm late [P = .064]), confirming that the boundary between the junctional zone and outer myometrium is different with MR imaging versus US.
In 49 patients with obstructive airways disease and 15 normal subjects O2 and CO2 tension in arterial blood, vital capacity, maximal midexpiratory flow rate and forced expiratory volume were studied at 524, 1,600, and 2,844 m altitude. There was an acute decrease in O2 and CO2 tension and an increase of maximal midexpiratory flow rate. After an adaptation period of 10-12 days to 1,600 m in 70% of the patients an increase of the O2 tension and a decrease of the airways obstruction was observed. 30 % of the patients showed during this period a further decrease in the O2 tension without significant changes in airways obstruction
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