Secular changes in body mass index (BMI) and cardiorespiratory fitness (20 m shuttle-run test performance) were assessed in 10-year-old children from an affluent area of England in 1998 (n = 303; 158 boys and 145 girls) and 2008 (n = 315; 158 boys and 157 girls). Girls' BMI did not change over the 10 year period. There was a significant increase in boys' BMI (p = 0.02). Cardiorespiratory fitness declined significantly (p<0.001) in both boys (7%) and girls (9%). This study shows a large and worrying decline in cardiorespiratory fitness in children from an affluent area of England.

No abstract

No abstract

SUMMARY A total of 117 patients with congenital adrenal hyperplasia who were under the care of paediatricians at Birmingham Children's Hospital between 1958 and 1985 were reviewed retrospectively. There were 47 boys (40%) and 70 girls (60%); 30 of the 47 boys (64%) and 38 of the girls (58% of the 66 whose salt state was known) were salt losers. In all salt losers the condition was diagnosed before the age of 6 months, 90% of the diagnoses being made during the first month. The ratio of boys to girls, the distributions of salt losers to non-salt losers, and the age at diagnosis were studied in relation to the year of birth. Early diagnosis was found to be more common in children born after 1970 due partly to the introduction of a method of assaying the concentration of 17a-hydroxyprogesterone in serum, partly to an increase in the number of paediatricians in the West Midlands, and partly to the appointment of a peadiatric endocrinologist. A neonatal screening programme does not seem to be necessary.