Fernando PHP, Panagoda GJ & Samaranayake LI? The relationship between the acid and alkaline phosphatase activity and the adherence of clinical isolates of Cundidu purupsilosis to human buccal epithelial cells. APMIS 1999;107: 1034-42. Cundidu purupsilosis is an emerging fungal pathogen implicated in many diseases, especially in compromised hosts. Candidal colonization and infection depends on the initial ability to adhere to host surfaces, which in turn depends upon the cell wall components and the allied structures of both the host and the fungus. Examination of a miscellaneous collection of 24 C. purupsi1osi.s isolates, from both superficial and deep infections, for their potential pathogenic traits displayed a relationship between the phosphatase activity measured with p-nitrophenol phosphate and adhesion of the yeasts to human buccal epithelial cells (BECs). Significant intraspecies differences were seen in both the alkaline and acid phosphatase activity as well as in their adhesion to BECs (p
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