This study considers that there is a significant rising tendency of MRONJ in non-oncological patients, what could be caused by underestimation of the risk for development MRONJ in these patients. There should be a better cooperation and information among dentists and doctors indicating the antiresorptive treatment and strong emphasis on primary prevention before the initial treatment even in non-oncological patients (Tab. 5, Fig. 7, Ref. 69).
A b s t r a c tThe aim of the study is the evaluation of the clinical outcome and effectiveness of the arthroscopic procedures of the temporomandibular joint (TMJ) in cases resistant to the conservative therapy. The monitored group consisted of 31 patients, who underwent the arthroscopy of the TMJ and have been followed up for 3 years. The followed up patients have underwent a MRI examination of TMJ. The authors evaluate the effectiveness of the treatment in relationship to the clinical picture, radiodiagnostical imaging methods and to the arthroscopy of the TMJ.
A b s t r a c tThe authors describe a case of a rare infectious disease of intra-articular tissues of the temporomandibular joint caused mainly by Pseudomonas aeruginosa. In scientific literature, under the heading invasive (malignant) external otitis, we can find cases of an infectious disease of the external acoustic meatus caused by a microbial agent of Pseudomonas aeruginosa which can subsequently penetrate into structures. However, a primary affliction of the abovementioned structures has not been described. Localisation and severity of the infection requires long-term and massive treatment with antibiotics.
A b s t r a c tThe direct oral anticoagulant drugs (DOAC) are generally safe and effective in several clinical settings including acute venous thromboembolic disease, prophylaxis in the postoperative setting, prevention of thromboembolism in patients with non-valvular atrial fibrillation, and in the management of acute coronary syndrome. The relatively short half-life, rapid onset of action, and predictable pharmacokinetics should simplify periprocedural use of the DOAC. The aim of this work is to propose and summarize periprocedural management of patients treated with the DOAC in dental practice and to inform about the principal specifications of this treatment.
A b s t r a c t Background. Osteonecrosis related to bisphosphonate therapy is a challenging disease with complicated treatment. It is well known among the maxillofacial surgeons all around the world since 2003. Despite of it, the incidence is still rising, because of the lack of prevention before using bisphosphonates. Disturbing the bone metabolism leads by even a small trauma to enormous defects, that is despite of intensive therapy irreversible. Treatment of this disease is commonly joint with losing the bone tissue and badly affects the quality of life. Often is necessary the combined therapy, surgery, antibiotics and antimycotics. The discontinuation of bisphosphonate treatment during the osteonecrosis therapy is also recommended if it is possible.Methods and results. We examined and treated 79 patients with bisphosphonate related osteonecrosis of the jaw. The comparison of several methods of treatment was made in all stages of disease, with research of the therapy length, complications together with the need of reoperation and following up all the patients during five years. The results of the therapy were in most cases satisfactory; only two patients had problems that persisted. None of the patients died because of this disease.Conclusions. Bisphosphonate related osteonecrosis of the jaw is a disease that is difficult to treat. For patient it costs too much, not because of using the expensive antibiotics, but mostly because it leads to the defects in patient's jaw, it is affecting the oral intake and the life of the patient at all. Prevention is the best way to discontinuation of the rising incidence, but it requires a cooperation of interested specialists and also perfect education of the patient.
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