The oxygen uptake efficiency slope (OUES) is a submaximal index incorporating
cardiovascular, peripheral, and pulmonary factors that determine the ventilatory
response to exercise. The purpose of this study was to evaluate the effects of
continuous exercise training and interval exercise training on the OUES in patients
with coronary artery disease. Thirty-five patients (59.3±1.8 years old; 28 men, 7
women) with coronary artery disease were randomly divided into two groups: continuous
exercise training (n=18) and interval exercise training (n=17). All patients
performed graded exercise tests with respiratory gas analysis before and 3 months
after the exercise-training program to determine ventilatory anaerobic threshold
(VAT), respiratory compensation point, and peak oxygen consumption (peak
VO2). The OUES was assessed based on data from the second minute of
exercise until exhaustion by calculating the slope of the linear relation between
oxygen uptake and the logarithm of total ventilation. After the interventions, both
groups showed increased aerobic fitness (P<0.05). In addition, both the continuous
exercise and interval exercise training groups demonstrated an increase in OUES
(P<0.05). Significant associations were observed in both groups: 1) continuous
exercise training (OUES and peak VO2 r=0.57; OUES and VO2 VAT
r=0.57); 2) interval exercise training (OUES and peak VO2 r=0.80; OUES and
VO2 VAT r=0.67). Continuous and interval exercise training resulted in
a similar increase in OUES among patients with coronary artery disease. These
findings suggest that improvements in OUES among CAD patients after aerobic exercise
training may be dependent on peripheral and central mechanisms.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.