6 While the membrane form of the receptor min immunostaining. Between 48 and 72 hours, the liver plays a role in lysosomal enzyme targeting and the gradually regained its normal appearance. As shown by promotion of cell proliferation, the role of the soluble Western blotting, in vitro differentiated FSCs released receptor remains enigmatic. It has been suggested that soluble receptor in the medium. Northern blot analysis release of soluble receptor is a mechanism of receptor showed this release to be preceded by an increased re-turnover and degradation 7 as well as a means of moduceptor-mRNA expression, whereas immunostaining lating the activity of the receptor ligands present in showed an increase of intracellular receptor. In conclu-the extracellular space. 8 Recently, the age and tissue-specific pattern of soluble receptor release from rat tissue explants in culture Abbreviations: IGF-II/M6P, insulin-like growth factor-II/mannose 6-phosphate; TGF-b, transforming growth factor b; FSC, fat-storing cell; GBSS, Gey's was examined. 8 The highest release of receptor in adult
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