Atherosclerosis is a life threatening cardiovascular disease causing lipoprotein accumulation within intima layer of artery wall and thus its thickening. Later stages are characterized by plaque formation with a lipid core separated from lumen by fibrous cap. In case of carotid arteries (CA), rupture of the plaque often results in a stroke. Detailed understanding of mechanical properties of atherosclerotic arteries and their components is essential for improvement of computer models used for prediction of plaque rupture. Samples of atherosclerotic CA from carotid endarterectomy were kept either in saline solution or in formaldehyde solution and then underwent uniaxial tensile testing in two directions. Statistical analysis of the obtained stressstrain responses shows that formaldehyde treatment of the tissue increases significantly the mean stiffness and reduces the dispersion.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.