Introduction:  Nanotechnology is a rapidly developing interdisciplinary area that has brought enormous changes in dentistry. Copper nanoparticle made from plant extract would be an environmental friendly, convenient and dependable way for providing therapeutic agents that are safe, free of side effects and useful for a wide range of diseases. Mucuna pruriens seed extract was selected for our study, due to its due to its anti- bacterial, anti-diabetic, anti- Parkinson, anti-cholesterol and anti- oxidant properties. Aim: To evaluate the anti-inflammatory properties of Mucuna pruriens, the green synthesis, characterization of CuNPs, and screening of their cytotoxic activity. Materials and methods: The collection and preparation of Mucuna pruriens extract was done and stored for further use. Synthesis of Cu nanoparticles was done with 30 milli molar of copper (II) sulfate. Centrifugation was done and characterisation of Copper nanoparticles using ultraviolet (UV)-visual spectrophotometer.  Cytotoxic effect and anti-inflammatory activity of copper nanoparticles with Mucuna pruriens seed extract were assessed using Brine Shrimp Assay at 5µL, 10µL, 20µL, 40µL and 80 µL and Bovine Serum Albumin (BSA) at 5 µL, 10 µL, 20 µL, 30 µL, 50 µL. Results: The anti inflammatory activity of Copper Nanoparticles with Mucuna pruriens, increased with increase in concentrations. Percentage of inhibition was 17% at 10 µL concentration, 24% at 20 µL, 43% at 30 µL and 54% at 40 µL and highest at 50 µL (71%). Cytotoxicity of Copper Nanoparticles with Mucuna pruriens, at 5 µL concentration there was a death of 10% of nauplii, at 10 µL there was a death of 20% of nauplii, at 20 µL and 40 µL there was a death of 30% of nauplii and at 80 µL there was a death of 40% of nauplii. As the concentration increased, the cytotoxicity of the nanoparticles increased. Conclusion: Based on the results of the current study, it is concluded that Mucuna pruriens mediated Cu Nps can be used as a potential source of anti inflammatory agent and also as an anti cancer drug for the treatment of tumours and cancers.

Nanotechnology has become one among the promising approaches for innovations which fulfil the human needs. Nanoparticles even have many applications in several fields like nanocomposites, medical imaging, nanobiocomposite filters, targeted drug delivery and hyperthermia of tumours. In which Selenium is an important micronutrient for living organisms. These nanoparticles are safe, eco friendly, inexpensive and nontoxic. Enterococcus faecalis  is an emergent gram - positive opportunistic pathogen that is the causative agent of several nosocomial infections and surgical wound infections. Therefore, it is becoming increasingly necessary to find other alternative treatments than commonly utilized drugs. The purpose of this study is to assess the antibacterial activity of Capparis decidua  fruit mediated selenium nanoparticles( cds-se Nps ) against Enterococcus faecalis. In this experimental study Se Nps were prepared by the reaction of 30mM sodium selenite solution and extracts of Capparis decidua. Antibacterial activity of SeNPs was assessed by using a disc diffusion method against Enterococcus faecalis. The SeNPs were characterized by UV-visible spectrophotometers. In the present study, the zone of inhibition shows 32mm, 35 mm, 37mm and 30 mm at concentration of 50 microliter, 100 microliter, 150 microliter and antibody respectively. The Capparis decidua  fruit mediated SeNp showed a good antibacterial activity against the pathogen Enterococcus faecalis

Dentists have a crucial role within the best prevention measures, controlling etiological factors and early detection. Lack of general dentist carcinoma knowledge has been shown to be a serious factor to delays in referral and treatment. Dentists’ competence and confidence in detecting carcinoma could also be strongly influenced by their school of dentistry training. Hence, it's the responsibility of the school of dentistry to make sure the formation of a generalist with solid technical, scientific, ethical knowledge, promoting good oral hygiene and prevention of oral diseases. Therefore, the aim of this study was to assess dental student’s awareness, role in preventing and early detection of oral cancer. The study population included 100 dental students. The data was collected and statistically analysed. In this present study, 48% male and 52% female participated. Here, 76% of scholars are conscious of carcinoma whereas 24% of scholars are unaware of oral cancer. The risk factors for carcinoma mainly described by the scholars were 44% for smoking and 8% for alcohol consumption. Most of the scholars considered that labial/ buccal mucosa was the commonest site in diagnosis of oral cancer. The early detection of carcinoma improves survival, which was suggested by 46% of scholars. About 59% of scholars reported that they need sufficient knowledge regarding prevention and management of carcinoma. In this present study, out of 100 Dental students who participated in awareness of carcinoma, majority of the dental students were aware and had better knowledge on preventive measures of oral cancer. This study also highlights the necessity for an improvement of the teaching program regarding oral examination.

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