The peritoneum is the main recurrence site in both early and advanced ovarian cancer. Initial disease spread and extent of surgery are associated with the recurrence risk. This article supports the view that more attention should be directed toward extensive treatment of the peritoneum.
The objective of this study was to evaluate the quality of life (QOL) of patients with
deep infiltrating endometriosis (DIE) using EuroQOL (EQ-5D) and its correlation
with symptoms and locations of endometriotic lesions.
One hundred and fifty-nine patients referred for DIE from January 2011 to April 2011
were prospectively invited to complete questionnaires evaluating symptoms
associated with endometriosis as well as the EQ-5D questionnaire and health state.
Patients also had locations of DIE evaluated by clinical examination and magnetic
resonance imaging (MRI).
All 159 patients completed the questionnaires. Item response rate was 91.1%. The
most intense symptoms were dysmenorrhea (7.1/10), painful defecation (6.3/10), and
fatigue (6.0/10). Mean (SD) scores were 77 (14) for the EQ-5D questionnaire and
63.4 (21) for the health state. A relation was observed between the EQ-5D
questionnaire and the presence of dysmenorrhea, dyspareunia, cyclic pelvic pain,
painful defecation, and diarrhea or constipation. Vaginal and rectal infiltrations were
significantly associated with altered EQ-5D and health state scores.
The EQ-5D questionnaire is easy to complete and well related to symptoms of DIE.
Rectal and vaginal infiltrations were found to be determinant factors of altered QOL
by the EQ-5D questionnaire and health state.
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