Background
Leiomyomas are benign smooth muscle tumours predominantly found in the uterus. Rarely, they may be located in the ovaries, scrotum, bladder, lungs, vascular structures and spermatic cord.
Case presentation
We managed a 39-year-old man who presented with a year history of progressive right-sided hemiscrotal swelling. The right scrotal mass was excised, and histology showed scrotal leiomyoma.
Conclusion
Scrotal leiomyoma is very rare and challenging to diagnose pre-operatively as a cause of scrotal swelling, but it is amenable to surgical excision.
Introduction and importance
Benign fibroblastic proliferation located within the scrotum are uncommon. They are also identified as fibrous pseudotumour and usually arise from the paratesticular region. Their pathogenesis is unknown. These tumours are difficult to diagnose pre-operatively and resemble intra-scrotal malignancy.
Case presentation
We managed a 26-year-old Nigerian man with a five-year history of left sided hemiscrotal swelling. The mass was excised, and histology showed benign fibroblastic proliferation.
Discussion
Most paratesticular tumours are benign. Imaging studies that show the mass as separate from the testis, normal levels of tumour markers and clinical features not suggestive of malignancy make the case for organ-sparing mass excision, in the treatment of paratesticular fibrous pseudotumour, very strong.
Conclusion
Intra-scrotal benign fibrous proliferation is a challenge to diagnose pre-operatively but excision of this benign mass without an orchidectomy is practicable when pre-operative assessment suggests a benign disease.
For years, Lactobacilli have been used as probiotics. They are believed to play important role in maintaining a state of immunological homeostasis within host. This research was aimed at evaluating immunity-boosting potential of lactic acid bacteria isolated from kunu and palm wine; using standard experimental/scientific methods. Results revealed the bacterial isolates, Lactobacillus fermentum, Lactobacillus plantarum, Lactobacillus acidophilus and Lactobacillus casei to influence the immune system of pathogen-infected albino Wister rats. The pathogen treated rats without probiotic did not survive shortly after the post-acclimatization treatment, while the pathogen treated rats (fed with probiotic) survived; with a mean weight ranging from 128.33 g – 149.19 g for pathogen treated rats, 140.18 g – 149.65 g for Lactobacillus species + pathogen treated rats and 150.90g – 188.31g for control rats (non-infected). The haematological parameters (PCV and Hb) of the Lactobacillus species + pathogen treated rats (ranging 45.6 – 53.4 %; 15.5 -17.8 mg/dl) were higher compared to the control rats (ranging 20.7 – 32.9 %; 6.9 – 11.0 mg/dl). Enzymes (AST and ALT) activities of the Lactobacillus species + pathogen treated rats ranged from 0.091 - 0.108 U/L and 0.092 – 0.094 U/L respectively; and the control rats ranged from 0.083 – 0.098 U/L and 0.072 – 0.095 U/L respectively, with no significant difference. The histological examination of the rats’ liver showed hepatic changes in the pathogen treated rats, unlike those of the Lactobacillus species + pathogen treated rats and the control rats, suggestive of the beneficial role of Lactobacillus species in the pathogen treated rats. However, further in-vivo research to study a more encompassing health benefits and the mechanism of actions of these Lactobacillus species is recommended.
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