Mycobacterium avium complex (MAC) infection has not been reported as a major opportunistic infection among patients with AIDS in Latin America or Africa. In this study, 125 AIDS patients who had persistent fever, anemia, and leukopenia were examined among 2628 AIDS patients admitted to Instituto de Infectologia Emilio Ribas between May 1990 and April 1992. From the bone marrow aspirates of the 125 patients, MAC was isolated from 23 (18.4%) and Mycobacterium tuberculosis was isolated from 9 (7.2%). Between 1985 and 1990, only 11 MAC isolations among 60,000 cultures obtained from human immunodeficiency virus-seronegative patients were documented in São Paulo. Hence, the minimal estimated rate of MAC infection in AIDS patients in this city was 23/2628, or 0.88%. These findings suggest that MAC infection is an important opportunistic infection, especially among a subset of patients with AIDS in Brazil who have clinical characteristics and risk activities similar to those associated with MAC infections in North America and Europe.
Eleven c a s e s of SSPE from t h e r u r a l southeast were studied a t Duke from 1968-73. Eight p a t i e n t s had a h i s t o r y of measles immunization and 5 of these reportedly had antecedent n a t u r a l measles. The diagnosis was confirmed i n every case e i t h e r by t h e u l t r a s t r u c t u r a l demonstration of v i r u s nucleocapsids i n b a i n t i s s u e or t h e detection of anti-measles antibodies i n t h e CSF.Six of t h e p a t i e n t s had normal EEGs when f i r s t examined, an average of 6 months a f t e r t h e onset of i l l n e s s . This gmup d i d not d i f f e r from those with abnormal EEGs i n any important d e t a i l including age, sex, measles antibody t i t e r , s e v e r i t y o r duration of i l l n e s s o r t h e length of survival. A l l of t h e EEGs eventually became abnormal, 4 with t h e c l a s s i c a l suppression burst p a t t e r n considered d i a p o s t i c f o r SSPE. A t t h e time of t h e normal t r a c i n g , one patient had well developed mpclonus.These findings indicate t h a t a normal EEG i s common i n SSPE e v k when t h e c l i n i c a l disease is moderately advanced.This re-emphasizes the diagnostic importance& CSF measles antibcdies when other s t u d i e s a r e normal. Dept. of Ped. and Path., Univ. of Miami Sch. Med., Miami, Fla. COUNTERIMMUNELECTROPHORESISDuring a period of 18 months, 15 cases of S e r r a t i a s e p t icemia were i d e n t i f i e d i n the Neonatal I C U of a large county h o s p i t a l including two outbreaks of 5 and 4 cases each.Weight SurvivalfPatient Number Mortality Age a t Onset 2,500gm 5/13 61% 1 t o 15 days 2,500gm 112 8 days Both term infants were postoperative p a t i e n t s (TE-fistula).An epidemiologic survey of the Neonatal I C U (8 beds) and the adjacent premature nurseries (35 beds) revealed:Equipment: 51230 c u l t u r e s grew S e r r a t i a Personnel: 2/67 ( 2 nurse's hands) Infants : 91238 ( 5 NP,3 r e c t a l , 1 eye). Control measures included s t r i c t hand washing with change from hexachlorophene t o a povidone-iodine preparation, elimination of water i n i s o l e t t e s , and r i n s i n g of hands, i s o l e t t e s and other equipment with 2% a c e t i c acid. Gentamycin replaced kanamycin i n accordance with the s e n s i t i v i t i e s . Two premat u r e i n f a n t s with meningitis survived a f t e r treatment with systemic and i n t r a t h e c a l gentamycin.I n a nursery epidemic of s e p s i s and meningitis due t o S e r r a t i a marcescens, s i g n i f i c a n t morbidity and mortality was seen i n premature and ill neonates. This emphasizes t h e importance of considering any microorganism a s a p o t e n t i a l devastating pathogen i n susceptible populations. During an outbreak of serogroup C sulfonamide-resistant controls. All infections occurred in infants with high abnormal colonNeisseria meningitidis i n the c i t y of Sao Paulo, Brazil, ization and were due to the type of bacterium producing the high colserogroup C meningococcal polysaccharide was given t o...
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.