Platelet-rich plasma injections may be considered for the temporary symptomatic relief of mild carpal tunnel syndrome.
ÖZET Amaç: Bu çalışmada 50 yaş üzeri osteoporozu olan ve olmayan olgularda osteoporoz için jinekolojik risk faktörlerini değerlendirmek amaçlanmıştır. Gereç ve Yöntem: Çalışmaya postmenopozal-senil osteoporoz tanısı alan 127 hasta ve 53 osteoporozu olmayan gönüllü alındı. Katılımcılar yaş, vücut kitle indeksi (VKİ), menarş yaşı, menopoz yaşı, doğum sayısı, düşük-küretaj sayısı, emzirme hikayesi gibi jinekolojik risk faktörleri açısından sorgulandı. Bulgular: Hastaların yaş ortalaması kontrollere göre daha yüksek, VKİ değerleri daha düşüktü (p<0,05). Menopoza girme yaşı hastalarda daha düşük, 12 ay ve üzeri emzirme oranı ise daha yüksekti (p<0,05). Hasta grubunun menapoz yaş ortalaması kontrol grubundan anlamlı olarak düşük bulundu (p<0,05). Bununla birlikte hasta ve kontrol grupları arasında menarş yaşı, doğum sayısı, düşük-küretaj sayıları açısından anlamlı bir fark saptanmadı (p>0,05). Hasta grubunda emziren 117 katılımcının 100'ü (%85.5), kontrol grubunda emziren 51 katılımcının ise 34'ü (%66.7) 12 ay ve üzeri sürede emzirmişti, istatistiksel olarak bu fark anlamlı bulundu (p<0,05). Sonuç: Osteoporoz için jinekolojik risk faktörlerinin belirlenmesi, gerekli önlemlerin alınması ve bu konudaki bilincin artırılması ile osteoporoz nedeniyle oluşabilecek kırıklardan doğan mortalite ve morbidite oranları azaltılabilir. Anahtar Kelimeler: Osteoporoz; Menopoz; Menarş ABSTRACT Objectıve: To evaluate gynecological risk factors in patients with and without osteoporosis who are older than 50 years of age. Material and Methods: One hundred and twenty seven patients with postmenopausal-senile osteoporosis and 53 non-osteoporotic volunteers were included. The subjects were examined in terms of age, body mass index (BMI), risk factors like age at menarche, age at menopause, number of births, numbers of miscarriage and curettage, and history of breast-feeding, Results: The mean age was statistically higher and the mean BMI level was statistically lower in patients (p<0,05). The mean menopause age was significantly lower, and the breast-feeding period equal or more than 12 months was significantly higher in patients (p<0,05). The mean age at menopause in the patient group was significantly lower (p<0,05). However, there was no difference between the patient and the control groups in terms of age at menarche, number of births, numbers of miscarriage and curettage (p>0,05). Hundred out of 117 patients (85.5%) breastfed equal or more than 12 months; 34 out of 51 volunteers (66.7%) breastfed equal or more than 12 months. This difference was found to be significant (p<0.05). Conclusıon: Finding the gynecological risk factors leading to osteoporosis, taking necessary precautions, and increasing the consciousness can decrease the morbidity and mortality ratios of fractures.
Objective: Osteoarthritis (OA) is the most common form of arthritis, resulting from the degradation of articular cartilage, degradation and proliferative reformation of subchondral bone and a low degree of synovitis that leads to a reduced quality of life. There is no established cure for knee OA. Treatment modalities which have an effect on the underlying biological processes responsible for OA pathogenesis may have potential. One such modality drawing attention is platelet-rich plasma (PRP) injections. In this study, we aimed to evaluate the effects of PRP injections retrospectively in patients with knee OA and the outcomes of two different volume injections. Materials and Method: A total of 314 patients were included in the study. After baseline physical examination, each patient was evaluated with VAS score and WOMAC before the procedure. All the patients received two intra-articular injections one month apart with autologous PRP and were followed up for a minimum period of 1 year (range, 12-34 months). Two weeks after the injections, the physical examinations of the patients and their evaluations with VAS scores and WOMAC criteria were repeated. Results: Both VAS scores and WOMAC scores showed significant differences after the first injection (p<0.05). Although both scores increased after the second injection, the differences were not significant (p>0.05). We also showed that as BMI increased both VAS scores and WOMAC scores increased. Conclusion: Although our study showed that PRP injections have favorable improvements in the management of knee OA such as reducing the pain and decreasing joint stiffness, PRP injections in the treatment of knee OA needs more standardized research.
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