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Introduction Episodes of bleeding in patients with haemophilia (PwH) are associated with haemophilic arthropathy, limitations in physical performance, reduced quality of life (QoL), and gait disorders. Aim This non‐randomized, controlled, interventional, prospective, single‐centre pilot study aimed to assess the effects of an 8‐week supervised therapeutic exercise program on musculoskeletal health, gait kinematic parameters (GKP), functional capacity, and QoL in adult PwH. Methods Nineteen PwH were allocated to an exercise group (n = 10) or a control group (n = 9). The patients in the exercise group followed an 8‐week supervised therapeutic exercise program. The Haemophilia Joint Health Score (HJHS), a two‐dimensional video‐based gait kinematic analysis (2D‐GKA), the 6‐min walking test (6MWT), and the Haemophilia Quality of Life Questionnaire for Adults (Haem‐A‐Qol) were used as the outcome measures at baseline, after the exercise program (at the 8th week), and at the 6th‐month follow‐up. Results A significant improvement was observed in the exercise group in the HJHS‐Total and Haem‐A‐Qol Total scores and the 6MWT value after the exercise program. Moreover, the 2D‐GKA revealed improvement in most of the GKP (knee extension during the midstance and late swing phases, ankle dorsiflexion during the midstance phase, and ankle plantar flexion during the preswing phase). However, the gain obtained by the exercise program was not maintained at the 6th‐month follow‐up for the HJHS‐Total and Hem‐A‐QoL‐Total scores and GKP. Conclusion The 8‐week supervised therapeutic exercise program was successful in achieving improvement in joint health, GKP, functional capacity, and QoL in PwH.

Background and aims The aim of this study was to evaluate changes in fat oxidation rate during 40 min of continuous exercise and identify the intensity at the highest fat oxidation rate (Fatmax). Methods A total of 14 sedentary males with age, body height, weight, and BMI averages of 29.3 ± 0.7 years, 178.3 ± 1.7 cm, 81.1 ± 3.9 kg, and 25.4 ± 0.9 kg/m2, respectively, were included in the study. Fatmax was determined using an indirect calorimeter with an incremental treadmill walking test at least after 12 h of fasting. On a separate day, at least after 12 h of fasting, the participants walked for 40 min within their predetermined individual Fatmax heart rate and speed ranges. Results The initial fat oxidation rate was not sustained within the first 16 min of exercise and was reduced; however, carbohydrate oxidation reached a stable level after nearly 10 min. Conclusions In sedentary individuals, during low-intensity physical activity, fat oxidation rates may not be sustainable as expected from Fatmax testing. Therefore, when exercise is prescribed, one should consider that the fat oxidation rate might decrease in sedentary overweight individuals.

BACKGROUND: Sprint drills are part of the soccer training routine for their resemblance to match activities. There is a lack of information in the literature about the changes in isokinetic skeletal muscle strength in response to sprint training. OBJECTIVE: This study evaluates the effects of eight weeks, on-season repeated sprint training with a change of direction on isokinetic strength parameters in well-trained youth soccer players. METHODS: Nineteen well-trained youth soccer players volunteered to participate in the study. The training program included three sets of six, 40 m (20 + 20 m) shuttle sprints twice a week for eight weeks. Isokinetic peak moment, work, and power of knee extensors and flexors were measured at angular velocities of 60, 180 and 240∘/s. Pre- and post-training valid isokinetic sector data were compared. RESULTS: Following the training period, dominant and non-dominant legs’ peak moment, work, and power values for both extensor and flexor muscle groups improved significantly at various angular velocities. CONCLUSIONS: Isokinetic strength enhancement may be explained with the induction of muscle hypertrophy following a prolonged period of sprint training.

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