Kinetic studies are reported for the electrophilic amination of substituted phenylmagnesium bromides and CuCN-catalyzed phenylzinc chlorides with acetone O-(2,4,6-trimethylphenylsulfonyl)oxime in tetrahydrofuran at reflux temperature and at room temperature respectively. Substituent effects were determined by competition experiments. Rate data are analyzed via Hammett relationships to support the proposed mechanisms for the substitution of these organometallics with an electrophilic amino transfer reagent.
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