Mammary tumors are the most common tumor type both in women and in female dogs. In women, heritable breast cancers have been linked mutations in the breast cancer susceptibility gene BRCA2 and it contains eight BRC repeats in exon 11 that bind to RAD51. In this study, we investigated the sequence variations of BRC1-BRC8 and C-terminus of canine BRCA2 gene. From a total of 64 canine patients with mammary tumors, 31 mammary tumors with benign and malign carcinomas and the 3 normal mammary glands were used for the study. In this study, 19 SNPs of exon 11 of BRCA2 in canine mammary tumors were detected for the first time. The c.2383A>C (T1425P) SNP was found to be the most probable disease-associated nsSNP. Our findings suggest that T1425P variation in BRC3 to be the most probable disease-associated nsSNP and may affect RAD51 binding strength.
Seker, I., Bayraktar, M., Kul, S. and Ozmen, 0. 2007. Effect of slaughter age on fattening performance and carcass characteristics of Japanese quails (Coturnix coturnix japonica). J . Appl. Anim. Res., To determine the most economic slaughter age for male Japanese quails a total of 220 quail chicks were fed a standard feed up to 49 days. Rate of live weight gain started decreasing after 28 days of age. Feed consumption showed similar trend after d35. However, the feed required for each gram of weight gain exhibited steep increase after d42. Dressing percentage was the highest when the birds were slaughtered on d35. Considering these results the slaughter of male Japanese quails is recommended at 42 days of age.
The occurrence of mastitis could be related to specific ultrasonographic teat measurements (e.g. CD, OTD and FTD) and these may be important in the breeding of cows with a predisposition to mastitis, as well in the evaluation of in-herd cows in terms of udder/teat deformities.
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