KUKAI is a pico-satellite developed by Kagawa University and was launched by the H-IIA rocket by the Japan Aerospace Exploration Agency (JAXA) on 23 January 2009. The primary objective of KUKAI is technical verification of a tethered space robot, which is a new type of space robot system proposed in previous work. KUKAI consists of mother and daughter satellites for tether deployment. This was the first time to launch mother-daughter satellite among pico-satellites less than 10kg in the world. Then, it is important to develop separation mechanism. The separation and the launch lock mechanisms for KUKAI have been developed, and confirmed and evaluated by launch environment and microgravity condition. As the launch result, KUKAI was separated from the rocket as planned, the system started normally, and deployment of the solar paddle and the antenna was succeeded.
Objective Tsushima mamushi (Gloydius tsushimaensis) is an endemic species of snake inhabiting only Tsushima Island, a remote Japanese island. We conducted a multicenter, retrospective study of G. tsushimaensis bites for the first time and developed a therapeutic algorithm that unified treatment on the island and is still in use today. Methods This is a multicenter, retrospective study comparing 72 cases from January 2005 to December 2018, before the introduction of the algorithm, and 12 cases from January 2019 to December 2020, after its introduction. Results There was no significant decrease in the maximum grade of symptoms after the introduction of the algorithm, but there was a decreasing trend (p=0.057). Conversely, the median of the maximum creatinine kinase levels was 343.5 IU/L (interquartile range: 115.5-4,745.5) before the algorithm's introduction and significantly lower (142.5; interquartile range: 111.3-163) after the algorithm's introduction (p=0.042). After the algorithm's introduction, the disseminated intravascular coagulation merger rate and the acute kidney injury incidence both dropped to 0%, from 9.7% and 6.9%, respectively, before the algorithm's introduction. There was no significant difference in the length of hospital stay before versus after the algorithm's introduction. Conclusion This study showed that the treatment algorithm can be safely and quickly applied. The algorithm's effectiveness is expected be strengthened by the accumulation of more cases in the future.
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