Background: Emotional and behavioral problems have been noted in a considerable number of patients after open-heart surgery. However, great discrepancy exists in the literature regarding the frequency and the course of psychiatric symptoms, cognitive performance, and quality of life among those patients. This prospective study was designed to assess the pre-and postoperative psychiatric profile, as well as the quality of life of patients undergoing open-heart surgery. Methods: One hundred patients who were prepared for cardiac surgery and met our selection criteria were recruited in this study. Each patient was subjected to the Hospital Anxiety and Depression Scale, the Mini-Mental State Examination with selective subtests of Wechsler Adult intelligence scale, and the Short Form 36 questionnaire to assess psychiatric symptoms, cognitive performance, and quality of life respectively. Assessment was done for each of the evaluated items before surgery as well as at 1 week and 6 months postoperatively. Results: The anxiety and depressive symptoms were significantly lower at 6 months postoperatively than preoperatively. The cognitive performance declined after 1 week, then improved significantly at the 6-month follow-up. The quality of life scale was significantly lower preoperatively than after surgery. Conclusions: Anxiety and depressive symptoms, which occurred in substantial percentage of patients undergoing open-heart surgery, were gradually improved with time. Cognitive functions showed early deterioration with significant improvement at 6 months. Psychiatric problems had an adverse impact on patients' quality of life which raised the importance of psychiatric consultation before and after cardiac surgeries to shorten recovery time.
Background: ADHD is one of the most common psychiatric disorders in children and adolescents. Altered functional connectivity has been associated with ADHD symptoms. This study aimed to investigate abnormal changes in the functional connectivity of resting-state brain networks (RSNs) among children and adolescents with different subtypes of ADHD. Methods: This study was performed on 50 participants Group A: included 30 children and adolescents with ADHD Group B: included 20 normal typically developing controls. All participants aged between 7 and 16 years. All study patients. All participants underwent a neuropsychological assessment by applying the DSM-5 criteria to them. All study children and adolescents will undergo a R-fMRI examination, including Blood oxygenation level dependent BOLD-MRI and pulsed Arterial spin labeling MRI (PASL-MRI). Results: According to Conner’s Rating scale, there was a significant difference between ADHD subtypes and severity. Children with combined subtype were more likely to have severe degree in both teacher and parent editions of Conner’s Rating Scale. On the other hand, children with inattentive subtype had less severe degrees by both teacher and parent edition. There were a statistically significance difference between both genders as regard ADHD severity according to Conner’s Rating scale (Teacher and parent editions) (P value = 0.049, 0.028 respectively). Males were significantly affected by moderate and severe type compared to females whose affection were mostly mild and moderate. According to CBCL, most of ADHD children had low competence parameters. There was a statistically significant difference (P value < 0.001) on the type of ADHD and social competence in the studied children, where the lowest parameters were found in children with hyperactive type. Conclusion: There was a statistically significant difference on the type of ADHD and social competence, where the lowest parameters were found in children with hyperactive type.
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