Background:A clinical evaluation of the L80 wave+ autorefractometer (Visionix Luneau, Chartres, France) was performed to evaluate its validity and repeatability compared with non-cycloplegic subjective refraction. The L80 wave+ autorefractometer is a new instrument based on the Hartmann-Shack principle that has a specific autorefraction function using the wavefront device and can also measure keratometry, topography of the cornea and higher-order aberrations. Methods: Refractive error measurements were obtained from 100 eyes of 50 subjects (age, 25 Ϯ 2.71 years) subjectively by one masked practitioner and objectively with the L80 wave+ autorefractometer (with a 3.0 mm pupil) by a second practitioner. Intra-test and inter-test (within a week after the initial objective measures) variability was assessed on 28 new subjects (56 eyes).