HighlightsRare case of 4 limb amputations due to peripheral gangrene from inotrope use.Contributing factors include disseminated intravascular coagulation and septic shock.Differential diagnoses include symmetrical peripheral gangrene and purpura fulminans.Some therapeutic agents are beneficial for peripheral ischemia with dopamine use.Single-stage elective amputations led to satisfactory rehabilitation with prosthesis.
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