This study investigated the effects of moonlighting on job satisfaction between academic staff and medical doctors in Southwest Nigeria. The study employed descriptive research design and multi-stage sampling technique to select the respondents. Questionnaire was adopted as the research instrument and it was administered to 393 academic staff and 348 medical doctors respectively across various Universities and hospitals in Southwest, Nigeria. The returned questionnaire were coded in Excel and IBM SPSS 23 version respectively and were further analysed through t-test, analysis of variance (ANOVA), and multivariate analysis of variance (MANOVA). The study revealed that moonlighting has positive and significant effect on job satisfaction whereas the academic staffs moonlight more often than medical doctors. The study concluded that It was suggested that Management of Universities and hospitals should develop Human Resources Management practices that has potency of satisfying their employees with the aim of getting them more committed to their primary duties and assignments. In this way, moonlighting will be drastically reduced among academic staff and medical doctors.
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