Background: Acute coronary syndrome (ACS) refers to clinical symptoms pertaining to acute myocardial infarction. Bilirubin is an antioxidant that helps in removal of excessive heme. The aim of the study was to find the association of ACS and other risk factors for ACS with the total bilirubin levels in our setup.Methods: A cross sectional observational study was conducted on 100 cases attending the department of medicine in a Dr. Panjabrao Deshmukh Memorial Medical College, Amravati, Maharashtra. Patients fitting the eligibility criteria were subjected to data collection which was done using pre-designed case record form. The case record form had details of demography, detailed clinical history, physical examination and relevant investigations.Results: The mean age of the cases was 55.64±10.23 years with male preponderance. Majority of the patients presented with chest pain (83%) followed by shortness of breath (65%) and nausea/vomiting (33%). There was moderate significant correlation between total bilirubin levels and LDL levels (r=0.703; p value<0.001) and There was mild significant correlation between total bilirubin levels and TGs (r=0.403, p value<0.001) Based on the median value of 0.48 as cut off, 33% had bilirubin levels more than 0.48. Presence of diabetes and hyperlipidemias had significant association with the total bilirubin levels.Conclusions: Nearly 1/3rd of the patients in our study had high bilirubin levels. Higher bilirubin levels correlated well with presence of diabetes and presence of hyperlipidemias. There was significant correlation between the serum LDL and TG levels with total bilirubin levels in the present study.
Background: Alteration of HbA1c in other conditions such as haemolytic anaemia, pregnancy and haemoglobinopathy has raised questions about its correlation with iron stores. The aim of the study was to correlate iron deficiency anaemia with glycosylated haemoglobin levels among non-diabetics.Methods: The present study was an observational study among non-diabetic patients of iron deficiency anaemia attending our outpatient department. The study was conducted in the department of medicine of a tertiary care hospital in Maharashtra. All the non-diabetic patients more than 18 years with iron deficiency anaemia were included in the present study. Patients with acute coronary syndromes, chronic liver, chronic kidney diseases, malignancies, haemolytic anaemia, pregnancy, HIV positive with known end stage cardiopulmonary disease were excluded from the study.Results: About 86.33% of the patients had mild to moderate anaemia and 10.7% had severe anaemia in the present study. The average values of haemoglobin, serum ferritin, total iron binding capacity, mean corpuscular volume, mean corpuscular haemoglobin, and mean corpuscular haemoglobin concentration and hematocrit significantly improved after the treatment. With treatment of anaemia, glycosylated haemoglobin, fasting blood sugars and post prandial blood sugars also improved significantly when compared to baseline (p<0.001).Conclusions: The average values of haemoglobin, serum ferritin, total iron binding capacity, mean corpuscular volume, mean corpuscular haemoglobin, and mean corpuscular haemoglobin concentration and hematocrit significantly improved after the treatment. With treatment of anaemia, glycosylated haemoglobin, fasting blood sugars and post prandial blood sugars also improved significantly when compared to baseline.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.