ArticleFluorinated Bambusurils as Highly Effective and Selective Transmembrane Cl À /HCO 3 À Antiporters Synthetic anion receptors can be used to transport ions across membranes. In this work, bambusuril macrocycles are demonstrated to be very efficient in exchanging chloride and bicarbonate ions, whereas exchange with nitrate is much slower. This is explained by the anion binding properties of the receptor. The high rates of transport by these bambusurils and mechanistic insight provided here represent an advancement toward the future therapeutic applications of synthetic anion carriers.
A new series of pyrano-chromene and pyrimido pyrano-chromene derivatives were synthesized starting from 2-amino-4-(1-naphthyl)-5-oxo-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile (6). The structures of the synthesized compounds were elucidated by spectral data. Compounds 6-11, 13-15 and 18 have been selected for an inhibitory activity screening against HIV-1 and HIV-2 in MT-4 cells.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.