Tartrazine is a colorant widely used in food products, drugs and cosmetics. The current study evaluates the effect of sub-chronic ingestion of tartrazine in drinking water at doses of 0, 0.1, 0.45, 1 and 2.5% for 13 weeks in mice. Our results show that female body weight gain and food consumption decreased in all treated groups, while fluid consumption increased. The red blood cell count, hemoglobin and hematocrit were increased in male 2.5% treated groups and the white blood cell count decreased in all treated groups. In both sexes of the 2.5% doses groups, total proteins, albumin, creatinine, urea, uric acid, total bilirubin, alkaline phosphatase and transaminases were higher. Histological examinations showed brain, liver and kidney damages in animals treated with 1 and 2.5% doses. We concluded that at doses of 1 and 2.5% in drinking water, tartrazine induces weight depression and adverse effects on brain, liver and kidney.
Carbon nanotubes (CNTs) are an exceptional class of nanoparticles owing to their excellent mechanical and electronic properties. They have been applied in various engineering applications. Numerous researchers have examined the effects of CNTs on human health and the environment from various perspectives. Although research in nanotoxicology and nanoecotoxicology is a societal priority, the required experimental methods and approaches are still in the early stages of development, thus presenting a scientific challenge. The current study provides an in-depth analysis of the micromechanical properties of nanocomposite materials consisting of carbon fibers, glass fibers, and CNTs embedded in an epoxy matrix. The analytical method employed is based on a generic approach. As per the results, the carbon-CNT/epoxy hybrid nanocomposite exhibits higher resistance toward mechanical stresses compared with other materials, such as the CNT/epoxy nanocomposite and glass-CNT/epoxy hybrid nanocomposite. These findings are corroborated by Kamae's study, which reports that the utilization of CNT material significantly enhances the interfacial bonding between the carbon fiber and epoxy matrix. The results obtained from this study reveal numerous promising materials that have the potential to be highly valuable in various emerging sectors of society.
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