Vivax malaria is long considered to have a benign course. It is known for multiple relapses and falciparum infection was associated with complicated malaria. However in the past few years there is a changing trend in the clinical manifestations of vivax malaria namely severe or complicated disease; sometimes even causing death. Objective: To study the hepatic dysfunction, renal dysfunction and incidence of thrombocytopenia in malaria in childhood in Bundelkhand region. Design: Observational study in a Pediatric ward of tertiary care hospital in Jhansi Material and Methods: 100 patients between the age groups of 1 to 15 yrs, whose peripheral smear were positive for malarial parasite have been included in the study group. A detailed history and clinical examination was followed by investigations like hemogram, platelet counts, general blood picture, reticulocyte count, serum bilirubin, SGOT, SGPT, serum alkaline phosphatase, blood urea, serum creatinine. Results: Raised level of SGPT, SGOT and total serum bilirubin seen were 31%, 30%, 53% respectively. In our study 11(11%) of cases had raised level of blood urea or serum creatinine or both. 88 cases (88%) had platelet count < 1.5 lac/mm3.
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