Background and objectives Although pockets of bioinformatics excellence have developed in Africa, generally, large-scale genomic data analysis has been limited by the availability of expertise and infrastructure. H3ABioNet, a Pan African bioinformatics network, was established to build capacity specifically to enable H3Africa researchers to analyse their data in Africa. Since the inception of the H3Africa initiative, H3ABioNet’s role has evolved in response to changing needs from the consortium and the African bioinformatics community. The network set out to develop core bioinformatics infrastructure and capacity for genomics research in various aspects of data collection, transfer, storage and analysis. Methods and results Various resources have been developed to address genomic data management and analysis needs of H3Africa researchers and other scientific communities on the continent. NetMap was developed and used to build an accurate picture of network performance within Africa and between Africa and the rest of the world, and Globus Online has been rolled out to facilitate data transfer. A participant recruitment database was developed to monitor participant enrolment, and data is being harmonized through the use of ontologies and controlled vocabularies. The standardized metadata will be integrated to provide a search facility for H3Africa data and biospecimens. Since H3Africa projects are generating large-scale genomic data, facilities for analysis and interpretation are critical. H3ABioNet is implementing several data analysis platforms that provide a large range of bioinformatics tools or workflows, such as Galaxy, the Job Management System and eBiokits. A set of reproducible, portable and cloud scalable pipelines to support the multiple H3Africa data types are also being developed and dockerized to enable execution on multiple computing infrastructures. In addition, new tools have been developed for analysis of the uniquely divergent African data and for downstream interpretation of prioritized variants. To provide support for these and other bioinformatics queries, an online bioinformatics helpdesk backed by broad consortium expertise has been established. Further support is provided by means of various modes of bioinformatics training. Conclusion For the past 4 years, the development of infrastructure support and human capacity through H3ABioNet, have significantly contributed to the establishment of African scientific networks, data analysis facilities and training programmes. Here, we describe the infrastructure and how it has impacted genomics and bioinformatics research in Africa.

In this data article, a robust data exploration is performed on daily Internet data traffic generated in a smart university campus for a period of twelve consecutive (12) months (January–December, 2017). For each day of the one-year study period, Internet data download traffic and Internet data upload traffic at Covenant University, Nigeria were monitored and properly logged using required application software namely: FreeRADIUS; Radius Manager Web application; and Mikrotik Hotspot Manager. A comprehensive dataset with detailed information is provided as supplementary material to this data article for easy research utility and validation. For each month, descriptive statistics of daily Internet data download traffic and daily Internet data upload traffic are presented in tables. Boxplot representations and time series plots are provided to show the trends of data download and upload traffic volume within the smart campus throughout the 12-month period. Frequency distributions of the dataset are illustrated using histograms. In addition, correlation and regression analyses are performed and the results are presented using a scatter plot. Probability Density Functions (PDFs) and Cumulative Distribution Functions (CDFs) of the dataset are also computed. Furthermore, Analysis of Variance (ANOVA) and multiple post-hoc tests are conducted to understand the statistical difference(s) in the Internet traffic volume, if any, across the 12-month period. The robust data exploration provided in this data article will help Internet Service Providers (ISPs) and network administrators in smart campuses to develop empirical model for optimal Quality of Service (QoS), Internet traffic forecasting, and budgeting.

The H3ABioNet pan-African bioinformatics network, which is funded to support the Human Heredity and Health in Africa (H3Africa) program, has developed node-assessment exercises to gauge the ability of its participating research and service groups to analyze typical genome-wide datasets being generated by H3Africa research groups. We describe a framework for the assessment of computational genomics analysis skills, which includes standard operating procedures, training and test datasets, and a process for administering the exercise. We present the experiences of 3 research groups that have taken the exercise and the impact on their ability to manage complex projects. Finally, we discuss the reasons why many H3ABioNet nodes have declined so far to participate and potential strategies to encourage them to do so.PLOS Computational Biology | https://doi.org/10.1371/journal.pcbi

Efficient broadband Internet access is required for optimal productivity in smart campuses. Besides access to broadband Internet, delivery of high speed and good Quality of Service (QoS) are pivotal to achieving a sustainable development in the area of education. In this data article, trends and patterns of the speed of broadband Internet provided in a Nigerian private university campus are largely explored. Data transmission speed and data reception speed were monitored and recorded on daily basis at Covenant University, Nigeria for a period of twelve months (January–December, 2017). The continuous data collection and logging were performed at the Network Operating Center (NOC) of the university using SolarWinds Orion software. Descriptive statistics, correlation and regression analyses, Probability Density Functions (PDFs), Cumulative Distribution Functions (CDFs), Analysis of Variance (ANOVA) test, and multiple comparison post-hoc test are performed using MATLAB 2016a. Extensive statistical visualizations of the results obtained are presented in tables, graphs, and plots. Availability of these data will help network administrators to determine optimal network latency towards efficient deployment of high-speed broadband communication networks in smart campuses.