and the ERN CRANIO Working Group on Craniofacial Microsomia Index Summary Chapter 1. Introduction 1.1 Incentive for making the guideline 1.2 Purpose of the guideline 1.3 Scope of the guideline 1.4 Relationship to other congenital facial malformations 1.5 Intended users of the guideline 1.6 About craniofacial microsomia 1.7 European Reference Networks Chapter 2. Methodology 2.1 Validity of the guideline 2.2 General information 2.3 Aim and target audience guideline 2.3.1 Aim of the Guideline 2.3.2 Target audience 2.3.3 Patient population 2.4 Steering group 2.5 Conflicts of interest 2.6 Patient perspectives 2.7 Implementation 2.8 Methods 2.8.1 Bottleneck analysis 2.8.2 Questions and outcomes 2.8.3 Literature search and selection of literature 2.8.4 Quality assessment of individual studies 2.8.5 Summary of literature 2.8.6 Quality of evidence 2.8.7 Formulating conclusions 2.8.8 Considerations 2.8.9 Formulating recommendations 2.8.10 Conditions (organisation of care) 2.8.11 Knowledge gap 2.8.12 Evaluation and authorisation phase Chapter 3. Diagnostic criteria for craniofacial microsomia 3.1 Based on which criteria is a child or adult with craniofacial microsomia diagnosed? Chapter 4. Screening, monitoring and indication for treatment 4.1 Breathing difficulties in craniofacial microsomia
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